Massachusetts Institute of Technology patent applications published on November 30th, 2023

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Summary of the patent applications from Massachusetts Institute of Technology on November 30th, 2023

Recently, the Massachusetts Institute of Technology (MIT) has filed several patents for various innovative technologies. These patents cover a range of fields, including oscillator design, multi-phase electrochemical cells, molybdenum-containing alloys, targeted gene modification, RNA-targeting CRISPR effectors, ttRNAs for editing and integrating polynucleotide sequences, and gastric resident electronics.

In the field of oscillator design, MIT has developed an oscillator that includes a cavity with an electrical conductor, an electrical insulator, and a heterostructure consisting of spin current source layers and magnetic material layers. This design allows for the oscillation of magnetic domains with the same phase when an electrical current is passed through the spin current source.

MIT has also focused on improving the performance and efficiency of electrochemical cells. Their patents cover various aspects of multi-phase electrochemical cells, including their design, construction, and operation. These cells are designed to have high relative densities and stability, making them suitable for various conditions. Additionally, MIT has developed innovative methods for producing molybdenum-containing alloys with added secondary and/or tertiary elements, enhancing their properties during the sintering process.

In the field of genetic engineering, MIT has filed patents for targeted gene modification and RNA-targeting CRISPR effectors. These inventions aim to provide more efficient and precise methods for modifying genes, inserting specific genetic material, disrupting gene transcripts, and editing nucleic acids. The combination of transposases, CRISPR-Cas components, and transposable elements allows for targeted and controlled manipulation of genetic material.

MIT has also developed ttRNAs for editing and integrating polynucleotide sequences. These ttRNAs consist of specific sequences and structures that enable more efficient and precise editing and integration of polynucleotide sequences.

Lastly, MIT has developed gastric resident electronics, devices, systems, and methods. These electronic resident structures are designed to be administered orally and remain inside the subject for at least 24 hours. They include electronic components and may also deliver pharmaceutical agents. The modular design of these devices allows for long gastric residence, and materials that degrade or dissolve determine when the device exits the subject.

Notable applications:

  • Oscillator design for synchronized magnetic domain oscillations.
  • Improved multi-phase electrochemical cells for enhanced performance and efficiency.
  • Molybdenum-containing alloys with added elements for improved sintering properties.
  • Targeted gene modification and RNA-targeting CRISPR effectors for precise genetic manipulation.
  • ttRNAs for efficient editing and integration of polynucleotide sequences.
  • Gastric resident electronics for long-term monitoring and drug delivery.



Patent applications for Massachusetts Institute of Technology on November 30th, 2023

GASTRIC RESIDENT ELECTRONICS (18316954)

Main Inventor

Robert S. Langer


NUCLEIC ACID-GUIDED NUCLEASES AND USE THEREOF (18249865)

Main Inventor

Feng Zhang


SITE SPECIFIC GENETIC ENGINEERING UTILIZING TRANS-TEMPLATE RNAS (18303533)

Main Inventor

Omar Abudayyeh


TYPE VI CRISPR ORTHOLOGS AND SYSTEMS (18334046)

Main Inventor

Feng Zhang


SYSTEMS, METHODS, AND COMPOSITIONS FOR RNA-GUIDED RNA-TARGETING CRISPR EFFECTORS (18322675)

Main Inventor

Omar Osama Abudayyeh


TYPE I CRISPR-ASSOCIATED TRANSPOSASE SYSTEMS (18248252)

Main Inventor

Feng Zhang


MOLYBDENUM-CONTAINING ALLOYS AND ASSOCIATED SYSTEMS AND METHODS (18365142)

Main Inventor

Christopher A. Schuh


LITHIUM SOLID ELECTROLYTE AND METHOD OF MANUFACTURE THEREOF (18361290)

Main Inventor

Yuntong Zhu


MULTI-PHASE ELECTROCHEMICAL CELLS AND RELATED SYSTEMS AND METHODS (18132596)

Main Inventor

Yet-Ming Chiang


Spin Torque Oscillator Maser (18193885)

Main Inventor

Luqiao LIU