20240053290. BIOSENSORS simplified abstract (PROGNOMICS LTD)

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BIOSENSORS

Organization Name

PROGNOMICS LTD

Inventor(s)

Daniele Doneddu of Swansea (GB)

Balakrishna Ananthoju of Swansea (GB)

Rakesh Kumar of Swansea (GB)

BIOSENSORS - A simplified explanation of the abstract

This abstract first appeared for US patent application 20240053290 titled 'BIOSENSORS

Simplified Explanation

The patent application describes a biosensor with a cavity between two substrates, a sensing structure with a functionalized active surface on one substrate, and a flow control structure on the other substrate that creates a fluid flow channel across the active surface.

  • The biosensor includes first and second substrates with a cavity in between.
  • A sensing structure with a functionalized active surface is on the first substrate within the cavity.
  • A flow control structure on the second substrate extends into the cavity, creating a gap for fluid flow across the active surface.
  • An inlet port is located at one end of the fluid flow channel, with an outlet port at the opposite end.
  • Fluid injected at the inlet port flows through the channel to the outlet port, exerting a shear force on the active surface.

Potential applications of this technology:

  • Medical diagnostics
  • Environmental monitoring
  • Food safety testing

Problems solved by this technology:

  • Improved sensitivity and accuracy in detecting target molecules
  • Enhanced control over fluid flow for efficient analysis

Benefits of this technology:

  • Increased reliability of biosensor measurements
  • Simplified and streamlined fluid handling processes
  • Potential for miniaturization and portability for on-the-go testing.


Original Abstract Submitted

a biosensor includes first and second substrates that define a cavity therebetween. a sensing structure, having a functionalized active surface is provided on the first substrate, within said cavity. a flow control structure is provided on the second substrate, which extends into the cavity, and a gap between the distal end of the flow control structure and the sensing structure provides a fluid flow channel across said functionalized active surface. the biosensor further includes an inlet port, adjacent the proximal end of the flow control structure, at one end of the fluid flow channel, and an outlet port at the opposite end of the fluid flow channel. the flow control structure is shaped and configured such that, in use, fluid injected at the inlet port flows into and through the fluid flow channel to the outlet port, thereby exerting a shear force on the functionalized active surface.