20240050274. PROXIMAL ULTRASONIC WATER PRESSURE DEVICE FOR ULTRAFINE GAUGE VITRECTOMY IN COMBINED SAMPLING AND DRUG DELIVERY DEVICE simplified abstract (Twenty Twenty Therapeutics LLC)

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PROXIMAL ULTRASONIC WATER PRESSURE DEVICE FOR ULTRAFINE GAUGE VITRECTOMY IN COMBINED SAMPLING AND DRUG DELIVERY DEVICE

Organization Name

Twenty Twenty Therapeutics LLC

Inventor(s)

Alexandre Tumlinson of South San Francisco CA (US)

Dimitri Azar of South San Francisco CA (US)

PROXIMAL ULTRASONIC WATER PRESSURE DEVICE FOR ULTRAFINE GAUGE VITRECTOMY IN COMBINED SAMPLING AND DRUG DELIVERY DEVICE - A simplified explanation of the abstract

This abstract first appeared for US patent application 20240050274 titled 'PROXIMAL ULTRASONIC WATER PRESSURE DEVICE FOR ULTRAFINE GAUGE VITRECTOMY IN COMBINED SAMPLING AND DRUG DELIVERY DEVICE

Simplified Explanation

The device described in the patent application is a tool for inserting into the vitreous humor of the eye. It includes a penetration member with a hollow body that can receive a liquid column and has at least one port. The distal end of the penetration member is designed for insertion into the vitreous humor.

The device also includes a pressure modulation system that is connected to the hollow body. This system consists of a low frequency modulation mechanism and a high frequency modulation mechanism. These mechanisms work together to draw the vitreous humor into the hollow body and liquefy it. The high frequency modulation mechanism applies acoustic pressure modulation to the liquid column at the proximal end of the penetration member, which is then transferred to the distal end.

  • The device is designed to be inserted into the vitreous humor of the eye.
  • It includes a hollow body with a lumen and at least one port.
  • The pressure modulation system helps draw and liquefy the vitreous humor.
  • The high frequency modulation mechanism applies acoustic pressure to the liquid column.

Potential applications of this technology:

  • Minimally invasive treatment of vitreous humor-related eye conditions.
  • Improved delivery of medication or therapeutic agents to the vitreous humor.

Problems solved by this technology:

  • Provides a less invasive alternative to traditional surgical procedures for treating vitreous humor-related conditions.
  • Allows for targeted delivery of medication or therapeutic agents to the vitreous humor.

Benefits of this technology:

  • Reduced risk and complications compared to traditional surgical procedures.
  • More precise and controlled delivery of medication or therapeutic agents.
  • Potentially shorter recovery time for patients.


Original Abstract Submitted

a device includes an eye penetration member extending from a proximal end to a distal end and including a body defining a lumen for receiving a liquid column and including at least one port extending to the lumen. the distal end is configured for insertion into the vitreous humor of an eye. a pressure modulation system is in fluid communication with the lumen and includes a low frequency modulation mechanism and a high frequency modulation mechanism that cooperate to draw vitreous humor into the lumen and liquefy the vitreous humor. the high frequency pressure modulation imparts acoustic pressure modulation to the liquid column at the proximal end of the eye penetration member which is transferred to the distal end of the eye penetration member.

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