20240043503. COMPOSITIONS AND METHODS FOR THE TREATMENT OF IMMUNODEFICIENCY simplified abstract (ADMA BIOMANUFACTURING, LLC)
COMPOSITIONS AND METHODS FOR THE TREATMENT OF IMMUNODEFICIENCY
Organization Name
Inventor(s)
Adam S. Grossman of Saddle River NJ (US)
James Mond of Silver Spring MD (US)
Jerrold B. Grossman of Saddle River NJ (US)
Dov A. Goldstein of New York NY (US)
COMPOSITIONS AND METHODS FOR THE TREATMENT OF IMMUNODEFICIENCY - A simplified explanation of the abstract
This abstract first appeared for US patent application 20240043503 titled 'COMPOSITIONS AND METHODS FOR THE TREATMENT OF IMMUNODEFICIENCY
Simplified Explanation
The present invention is about compositions and methods for treating immunodeficiency, specifically primary immunodeficiency disease. The invention provides human plasma immunoglobulin compositions that contain specific antibody titers for a variety of respiratory pathogens. It also includes methods for identifying human donors and donor samples for use in the compositions, manufacturing the compositions, and utilizing the compositions for prophylactic administration and/or therapeutic treatment, such as passive immunization.
- The invention focuses on treating immunodeficiency, particularly primary immunodeficiency disease.
- It provides human plasma immunoglobulin compositions with specific antibody titers for respiratory pathogens.
- Methods for identifying human donors and donor samples for the compositions are included.
- The invention also covers manufacturing the compositions and utilizing them for prophylactic administration and therapeutic treatment, such as passive immunization.
Potential Applications
This technology has potential applications in the field of immunodeficiency treatment, specifically primary immunodeficiency disease. It can be used to develop effective therapies for individuals with compromised immune systems, providing them with specific antibodies against respiratory pathogens.
Problems Solved
This technology addresses the problem of immunodeficiency, particularly primary immunodeficiency disease. It aims to provide a solution for individuals with weakened immune systems by offering specific antibody titers against a variety of respiratory pathogens.
Benefits
The benefits of this technology include:
- Improved treatment options for individuals with immunodeficiency.
- Specific antibody titers against respiratory pathogens can enhance the immune response.
- Prophylactic administration and passive immunization can help prevent and treat infections in immunocompromised individuals.
Original Abstract Submitted
the present invention relates to compositions and methods for the treatment of immunodeficiency (e.g., primary immunodeficiency disease). in particular, the invention provides human plasma immunoglobulin compositions containing select antibody titers specific for a plurality of respiratory pathogens, methods of identifying human donors and donor samples for use in the compositions, methods of manufacturing the compositions, and methods of utilizing the compositions (e.g., for prophylactic administration and/or therapeutic treatment (e.g., passive immunization (e.g., immune-prophylaxis))).
