20240027397. Systems and Methods for Capturing Full Resolution Ion Mobility Data and Performing Multi-Analyte Targeted Data Acquisition simplified abstract (MOBILion Systems, Inc.)
Systems and Methods for Capturing Full Resolution Ion Mobility Data and Performing Multi-Analyte Targeted Data Acquisition
Organization Name
Inventor(s)
John Daniel Debord of West Grove PA (US)
Liulin Deng of Chester Springs PA (US)
Zongyuan Chen of Claymont DE (US)
Systems and Methods for Capturing Full Resolution Ion Mobility Data and Performing Multi-Analyte Targeted Data Acquisition - A simplified explanation of the abstract
This abstract first appeared for US patent application 20240027397 titled 'Systems and Methods for Capturing Full Resolution Ion Mobility Data and Performing Multi-Analyte Targeted Data Acquisition
Simplified Explanation
The patent application describes a system for capturing full resolution ion mobility data. It includes an ion mobility separation device that receives ions, guides a portion of them, and separates them based on their mobility. An ion detector receives the ions and detects ions with a predefined mass-to-charge ratio during a specific time period, generating a responsive signal. A data acquisition system receives the signal from the detector and generates a time-dependent ion signal representing the intensity of the signal at different arrival time periods during the time period.
- The system captures full resolution ion mobility data.
- It separates ions based on their mobility using an ion mobility separation device.
- An ion detector detects ions with a specific mass-to-charge ratio during a defined time period.
- A data acquisition system generates a time-dependent ion signal representing the intensity of the detected ions at different arrival time periods.
Potential applications of this technology:
- Analyzing complex mixtures of ions in fields such as proteomics, metabolomics, and environmental analysis.
- Identifying and characterizing unknown compounds in various samples.
- Enhancing the accuracy and sensitivity of ion mobility measurements.
Problems solved by this technology:
- Overcoming limitations in traditional ion mobility techniques that may result in loss of resolution or sensitivity.
- Enabling the capture of full resolution ion mobility data, providing more detailed information about the analyzed ions.
Benefits of this technology:
- Improved understanding of complex mixtures of ions.
- Enhanced identification and characterization of unknown compounds.
- Increased accuracy and sensitivity in ion mobility measurements.
Original Abstract Submitted
a system for capturing full resolution ion mobility data includes an ion mobility separation device that receives ions, guides a portion thereof, and separates the guided ions based on mobility. an ion detector receives the ions, detects ions having a predefined mass-to-charge ratio during a time period, and generates a responsive signal(s). a data acquisition system receives the signal(s) from the detector and generates a time dependent ion signal representing intensity of the signal(s) at different arrival time periods during the time period. a system for performing multi-analyte targeted data acquisition includes an ion mobility separation device that receives a stream of ions, guides a portion of the ions, and separates the ions based on mobility. an ion detector receives the ions and switches from detecting a first mass-to-charge ratio during a first arrival time to detecting a second mass-to-charge ratio during a second arrival time of a first scan.
