20240024344. Methods For The Effective Treatment Of Metastatic Cancer simplified abstract (General Oncology, Inc.)

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Methods For The Effective Treatment Of Metastatic Cancer

Organization Name

General Oncology, Inc.

Inventor(s)

Arnold Glazier of Newton MA (US)

Methods For The Effective Treatment Of Metastatic Cancer - A simplified explanation of the abstract

This abstract first appeared for US patent application 20240024344 titled 'Methods For The Effective Treatment Of Metastatic Cancer

Simplified Explanation

The present invention is about methods for treating metastatic cancer by administering a set of drugs that overcome melphalan resistance and hypersensitize cancer cells to melphalan. These methods involve the administration of drugs that induce oxidative stress in cancer cells, along with melphalan, on a defined schedule.

  • The invention describes methods for treating metastatic cancer by combining drugs that induce oxidative stress in cancer cells with melphalan.
  • The drugs used in the treatment overcome melphalan resistance and make cancer cells more sensitive to melphalan.
  • The administration of the drugs and melphalan is done on a specific schedule.

Potential applications of this technology:

  • Treatment of metastatic cancer: The methods described in the patent application can be used to treat metastatic cancer by overcoming resistance to melphalan and sensitizing cancer cells to the drug.
  • Combination therapy: The invention involves combining drugs that induce oxidative stress with melphalan, which can potentially be applied to other types of cancer treatments as well.

Problems solved by this technology:

  • Melphalan resistance: The methods described in the patent application address the issue of resistance to melphalan, a commonly used chemotherapy drug.
  • Hypersensitizing cancer cells: The invention aims to hypersensitize cancer cells to melphalan, making them more susceptible to the drug's effects.

Benefits of this technology:

  • Improved treatment outcomes: By overcoming melphalan resistance and sensitizing cancer cells, the methods described in the patent application can potentially improve treatment outcomes for metastatic cancer patients.
  • Enhanced efficacy of melphalan: The combination of drugs that induce oxidative stress with melphalan can enhance the efficacy of the drug, leading to better cancer cell killing.


Original Abstract Submitted

the present invention relates to methods for the treatment of metastatic cancer. methods of treating metastatic cancer by administration of a set of drugs overcome multiple mechanisms of melphalan resistance and hypersensitize cancer cells to melphalan are described. the methods involve the administration of drug(s) that induce oxidative stress in cancer cells, in conjunction with melphalan on a defined schedule.