20240019419. MICROFLUIDIC-BASED BLADDER CANCER MIMIC AND USE THEREOF simplified abstract (CHUNG ANG UNIVERSITY INDUSTRY ACADEMIC COOPERATION FOUNDATION)

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MICROFLUIDIC-BASED BLADDER CANCER MIMIC AND USE THEREOF

Organization Name

CHUNG ANG UNIVERSITY INDUSTRY ACADEMIC COOPERATION FOUNDATION

Inventor(s)

In Ho Chang of Seoul (KR)

Joong Yull Park of Seoul (KR)

Se Young Choi of Seoul (KR)

MICROFLUIDIC-BASED BLADDER CANCER MIMIC AND USE THEREOF - A simplified explanation of the abstract

This abstract first appeared for US patent application 20240019419 titled 'MICROFLUIDIC-BASED BLADDER CANCER MIMIC AND USE THEREOF

Simplified Explanation

The abstract describes a patent application for a microfluidic bladder cancer mimic and its use in screening bladder cancer treatment substances. The bladder cancer mimic is produced using 3D printing, which allows for a more accurate representation of in vivo environments compared to conventional two-dimensional cell models. It is also simpler to produce than animal models. The lab-on-a-chip, which includes the bladder cancer mimic, can be used to develop anticancer therapeutic agents and patient-specific therapeutic agents using patient-derived bladder cancer cells.

  • The patent application describes a microfluidic bladder cancer mimic produced through 3D printing.
  • The mimic provides a more accurate representation of in vivo environments compared to conventional two-dimensional cell models.
  • The mimic is simpler to produce than animal models.
  • The lab-on-a-chip, including the bladder cancer mimic, can be used for screening bladder cancer treatment substances.
  • The technology can aid in the development of anticancer therapeutic agents.
  • The technology can be used to develop patient-specific therapeutic agents using patient-derived bladder cancer cells.

Potential Applications

  • Screening bladder cancer treatment substances
  • Development of anticancer therapeutic agents
  • Development of patient-specific therapeutic agents

Problems Solved

  • Lack of accurate representation of in vivo environments in conventional two-dimensional cell models
  • Complexity and limitations of animal models for bladder cancer research

Benefits

  • More accurate representation of bladder cancer in vivo environments
  • Simplified production process compared to animal models
  • Potential for personalized medicine using patient-derived bladder cancer cells


Original Abstract Submitted

a microfluidic bladder cancer mimic and the use thereof is provided. the bladder cancer mimic is produced through 3d printing, which may more accurately reflect in vivo environments than conventional two-dimensional cell models and may be more simply produced than animal models. a method of screening bladder cancer treatment substances using a lab-on-a-chip including the bladder cancer mimic that may be used for the development of anticancer therapeutic agents and may also be used to develop patient-specific therapeutic agents by using patient-derived bladder cancer cells.