20240018467. TAURINE SUPPLEMENTED CELL CULTURE MEDIUM AND METHODS OF USE simplified abstract (Regeneron Pharmaceuticals, Inc.)

TAURINE SUPPLEMENTED CELL CULTURE MEDIUM AND METHODS OF USE

Organization Name

Regeneron Pharmaceuticals, Inc.

Inventor(s)

Amy S. Johnson of Briarcliff Manor NY (US)

Meghan E. Casey of Ridgewood NJ (US)

Shadia Oshodi of Jersey City NJ (US)

Shawn Lawrence of Nyack NY (US)

TAURINE SUPPLEMENTED CELL CULTURE MEDIUM AND METHODS OF USE - A simplified explanation of the abstract

This abstract first appeared for US patent application 20240018467 titled 'TAURINE SUPPLEMENTED CELL CULTURE MEDIUM AND METHODS OF USE

Simplified Explanation

The patent application describes a composition for an improved eukaryotic cell culture medium that can be used to produce a specific protein. The addition of taxulne to the serum-free or chemically-defined media can enhance the production of the protein. The application also includes methods for expressing high levels of protein using these media compositions.

• The patent application describes a composition for an improved eukaryotic cell culture medium.
• Taxulne can be added to the serum-free or chemically-defined media to increase protein production.
• The application includes methods for expressing high levels of protein using the media compositions.

Potential Applications:

• Biopharmaceutical production: This technology can be used in the production of therapeutic proteins, antibodies, and other biopharmaceuticals.
• Research and development: The improved cell culture medium can be utilized in laboratories for protein expression studies and drug discovery.

Problems Solved:

• Low protein production: The addition of taxulne to the cell culture medium addresses the problem of low protein yields, allowing for higher production levels.
• Serum-free culture limitations: The composition provides an alternative to serum-containing media, which can have limitations and potential risks in certain applications.

Benefits:

• Increased protein production: The addition of taxulne to the cell culture medium enhances the production of the protein of interest, leading to higher yields.
• Versatile application: The improved cell culture medium can be used with different types of eukaryotic cells, making it applicable to various protein production processes.
• Serum-free option: The composition offers a serum-free alternative, reducing the potential risks associated with serum-containing media and providing more control over the cell culture conditions.

Original Abstract Submitted

the specification describes a composition comprising an improved eukaryotic cell culture medium, which can be used for the production of a protein of interest. taxulne can be added to the serum-free media or chemically-defined media to incrase the production of a protein of interest. methods for recombinantly expressing high levels of protein using the media compositions are included.