20240018130. Pyrimidine Derivative, Method For Preparing Same And Use Thereof In Medicine simplified abstract (Zhejiang Hisun Pharmaceutical Co., Ltd.)

Pyrimidine Derivative, Method For Preparing Same And Use Thereof In Medicine

Organization Name

Zhejiang Hisun Pharmaceutical Co., Ltd.

Inventor(s)

Lei Chen of Taizhou (CN)

Dongliang Guan of Taizhou (CN)

Hua Bai of Taizhou (CN)

Jun Gou of Taizhou (CN)

Weifeng Zhao of Taizhou (CN)

Zhongli Wang of Taizhou (CN)

Long Ling of Taizhou (CN)

Yutao Ma of Taizhou (CN)

Pyrimidine Derivative, Method For Preparing Same And Use Thereof In Medicine - A simplified explanation of the abstract

This abstract first appeared for US patent application 20240018130 titled 'Pyrimidine Derivative, Method For Preparing Same And Use Thereof In Medicine

Simplified Explanation

The present invention is about a pyrimidine derivative and its use in medicine. Specifically, it focuses on a pyrimidine derivative represented by a general formula (i), its preparation method, and a pharmaceutically acceptable salt of the derivative. The derivative is also described as a therapeutic agent, particularly as a fgfr4 kinase inhibitor. The abstract mentions that the definitions of each substituent in the general formula (i) are the same as those defined in the description.

• The invention is related to a pyrimidine derivative and its use in medicine.
• The derivative is represented by a general formula (i).
• The invention includes a method for preparing the pyrimidine derivative.
• A pharmaceutically acceptable salt of the derivative is also part of the invention.
• The pyrimidine derivative is described as a therapeutic agent, specifically as a fgfr4 kinase inhibitor.
• The definitions of each substituent in the general formula (i) are the same as those defined in the description.

Potential applications of this technology:

• Treatment of diseases or conditions where fgfr4 kinase inhibition is beneficial.
• Development of new therapeutic agents targeting fgfr4 kinase.
• Research and development in the field of pyrimidine derivatives and their medicinal uses.

Problems solved by this technology:

• Lack of effective fgfr4 kinase inhibitors in the market.
• Limited treatment options for diseases or conditions where fgfr4 kinase plays a role.
• Need for improved methods of preparing pyrimidine derivatives.

Benefits of this technology:

• Potential for improved treatment outcomes in diseases or conditions where fgfr4 kinase is involved.
• Possibility of developing more targeted and effective therapeutic agents.
• Expansion of knowledge and understanding in the field of pyrimidine derivatives and their medicinal uses.

Original Abstract Submitted

the present invention relates to a pyrimidine derivative, a method for preparing same and use thereof in medicine. in particular, the present invention relates to a pyrimidine derivative represented by general formula (i), a method for preparing same and a pharmaceutically acceptable salt thereof as well as use thereof as a therapeutic agent, in particular as a fgfr4 kinase inhibitor, definitions of each substituent in the general formula (i) being the same as those defined in the description.