20240018106. A PROCESS FOR THE PREPARATION OF SUBSTITUTED PYRIDINE COMPOUNDS AND INTERMEDIATES THEREOF simplified abstract (PI INDUSTRIES LIMITED)

A PROCESS FOR THE PREPARATION OF SUBSTITUTED PYRIDINE COMPOUNDS AND INTERMEDIATES THEREOF

Organization Name

PI INDUSTRIES LIMITED

Inventor(s)

Pranab Kumar Patra of Udaipur -Rajasthan (IN)

Suresh Kumar Sythana of Hyderabad (IN)

Pramod Nagle of Dist-Jalgaon-Maharashtra (IN)

Kantilal Balu Shende of Ahmednagar -Maharashtra (IN)

Vipender Singh of Uttar Pradesh (IN)

Alexander G.M. Klausener of Pulheim (DE)

A PROCESS FOR THE PREPARATION OF SUBSTITUTED PYRIDINE COMPOUNDS AND INTERMEDIATES THEREOF - A simplified explanation of the abstract

This abstract first appeared for US patent application 20240018106 titled 'A PROCESS FOR THE PREPARATION OF SUBSTITUTED PYRIDINE COMPOUNDS AND INTERMEDIATES THEREOF

Simplified Explanation

The present invention is a process for preparing substituted pyridine compounds. The process involves obtaining vinylogous nitriles from substituted α,β-unsaturated nitrile compounds and then converting the vinylogous nitriles into substituted pyridines.

• The process involves obtaining vinylogous nitriles from substituted α,β-unsaturated nitrile compounds.
• The obtained vinylogous nitriles are then converted into substituted pyridines.
• The substituted pyridine compounds are of formula (i), while the vinylogous nitriles are of formula (ii) and the α,β-unsaturated nitrile compounds are of formula (iii).
• The variables r, r, r, rand lg are defined in the description.

Potential applications of this technology:

• The prepared substituted pyridine compounds can be used as pharmaceutical intermediates.
• They can be utilized in the synthesis of various drugs and therapeutic agents.
• The compounds may have potential applications in the field of agrochemicals.

Problems solved by this technology:

• The process provides a method for efficiently preparing substituted pyridine compounds.
• It offers a convenient and reliable route for obtaining vinylogous nitriles from α,β-unsaturated nitrile compounds.
• The conversion of vinylogous nitriles into substituted pyridines allows for the synthesis of diverse compounds.

Benefits of this technology:

• The process allows for the synthesis of substituted pyridine compounds with high efficiency.
• It provides a versatile method for the preparation of pharmaceutical intermediates.
• The technology offers potential applications in the development of new drugs and agrochemicals.

Original Abstract Submitted

the present invention discloses a process for the preparation of substituted pyridine compounds of formula (i), comprises a step in which vinylogous nitriles of formula (ii), are obtained from substituted �,�-unsaturated nitrile compounds of formula (iii), and a further step of converting the vinylogous nitrile compounds of formula (ii) into substituted pyridines of formula (i); wherein r, r, r, rand lg are as defined in the description.