20240016439. GENERATING FUNCTIONAL BRAIN MAPPINGS AND ACCOMPANYING REFERENCE INFORMATION simplified abstract (SORA NEUROSCIENCE, INC.)
Contents
GENERATING FUNCTIONAL BRAIN MAPPINGS AND ACCOMPANYING REFERENCE INFORMATION
Organization Name
Inventor(s)
Eric C. Leuthardt of St. Louis MO (US)
Connor J. Burns of Louisville KY (US)
Patrick R. Campbell of Maryville TN (US)
Carl D. Hacker of St. Louis MO (US)
Stephen R. Schaefer of Minneapolis MN (US)
GENERATING FUNCTIONAL BRAIN MAPPINGS AND ACCOMPANYING REFERENCE INFORMATION - A simplified explanation of the abstract
This abstract first appeared for US patent application 20240016439 titled 'GENERATING FUNCTIONAL BRAIN MAPPINGS AND ACCOMPANYING REFERENCE INFORMATION
Simplified Explanation
The patent application describes a method for mapping functionally related brain regions of a subject using structural brain images and resting-state functional MRI (rs-fMRI) data. The method involves identifying groupings of functionally connected voxels and overlaying them on the structural brain image. The spontaneous brain activations of each voxel in a grouping are correlated with the activations of other voxels in the same grouping. A reference location map is generated to assist in identifying the resting state network of the functional connectivity map.
- The method uses structural brain images and rs-fMRI data to map functionally related brain regions.
- Groupings of functionally connected voxels are identified and overlaid on the structural brain image.
- The method correlates the spontaneous brain activations of voxels within a grouping.
- A reference location map is generated to assist in identifying the resting state network of the functional connectivity map.
Potential applications of this technology:
- Understanding brain connectivity and functional networks in healthy individuals.
- Identifying abnormalities or disruptions in brain connectivity in neurological disorders.
- Guiding surgical planning by mapping functional brain regions.
Problems solved by this technology:
- Provides a non-invasive method for mapping functionally related brain regions.
- Allows for the identification of resting state networks and their connectivity patterns.
- Helps in understanding the functional organization of the brain.
Benefits of this technology:
- Provides valuable insights into the functional connectivity of the brain.
- Can aid in the diagnosis and treatment of neurological disorders.
- Enables personalized medicine by mapping individual brain networks.
Original Abstract Submitted
a method for mapping functionally related brain regions of a subject. the method includes receiving a structural brain image and a dataset of resting-state functional mri (rs-fmr1) three-dimensional (3d) image frames of a brain of the subject includes 3d image frames of the subject's brain over time. a functional connectivity map identifying groupings of functionally connected voxels is overlaid on the structural brain image. spontaneous brain activations associated with each voxel in a grouping of functionally connected voxels are time-correlated with spontaneous brain activations in one or more other voxels in the grouping of functionally connected voxels. a reference location map for a pre-defined resting state network is generated, including reference information output. the reference location map includes brain reference locations that are informative of the one or more resting-state networks to assist a user in identifying the resting state network of the functional connectivity map.
