20240011081. Spatially Encoded Biological Assays simplified abstract (Prognosys Biosciences, Inc.)

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Spatially Encoded Biological Assays

Organization Name

Prognosys Biosciences, Inc.

Inventor(s)

Mark S. Chee of San Diego CA (US)

Spatially Encoded Biological Assays - A simplified explanation of the abstract

This abstract first appeared for US patent application 20240011081 titled 'Spatially Encoded Biological Assays

Simplified Explanation

The present invention relates to assays and assay systems used in spatially encoded biological assays. The invention provides an assay system that allows for high levels of multiplexing, where reagents are delivered to a biological sample in defined spatial patterns. The system includes instrumentation capable of controlled delivery of reagents according to the spatial patterns, as well as a decoding scheme that provides a digital readout.

  • Assay system for spatially encoded biological assays
  • High levels of multiplexing achieved
  • Reagents delivered to biological sample in defined spatial patterns
  • Instrumentation enables controlled delivery of reagents
  • Decoding scheme provides digital readout

Potential applications of this technology:

  • Biomedical research
  • Drug discovery and development
  • Disease diagnosis and monitoring
  • Genetic analysis and sequencing
  • Environmental monitoring

Problems solved by this technology:

  • Limited multiplexing capabilities in traditional assays
  • Inefficient use of reagents and samples
  • Lack of spatial information in assay readouts
  • Difficulty in analyzing complex biological samples

Benefits of this technology:

  • Increased throughput and efficiency in assays
  • Enhanced multiplexing capabilities
  • Spatially resolved information in assay readouts
  • Improved accuracy and sensitivity in biological analysis


Original Abstract Submitted

the present invention provides assays and assay systems for use in spatially encoded biological assays. the invention provides an assay system comprising an assay capable of high levels of multiplexing where reagents are provided to a biological sample in defined spatial patterns; instrumentation capable of controlled delivery of reagents according to the spatial patterns; and a decoding scheme providing a readout that is digital in nature.