20240010670. C19 SCAFFOLDS AND STEROIDS AND METHODS OF USE AND MANUFACTURE THEREOF simplified abstract (Trustees of Dartmouth College)
C19 SCAFFOLDS AND STEROIDS AND METHODS OF USE AND MANUFACTURE THEREOF
Organization Name
Inventor(s)
Glenn C. Micalizio of Norwich VT (US)
Arti B. Gaur of Hanover NH (US)
C19 SCAFFOLDS AND STEROIDS AND METHODS OF USE AND MANUFACTURE THEREOF - A simplified explanation of the abstract
This abstract first appeared for US patent application 20240010670 titled 'C19 SCAFFOLDS AND STEROIDS AND METHODS OF USE AND MANUFACTURE THEREOF
Simplified Explanation
The present disclosure relates to stereodefined polycyclic compounds that contain quaternary centers at one or multiple ring fusions. It also includes synthetic methods for preparing such compounds and methods of using them to treat diseases, particularly brain tumors such as gliomas.
- Stereodefined polycyclic compounds with quaternary centers at ring fusions
- Synthetic methods for preparing these compounds
- Methods of using these compounds to treat brain tumors, specifically gliomas
Potential Applications
- Treatment of brain tumors, particularly gliomas
- Pharmaceutical industry for developing new drugs
Problems Solved
- Lack of effective treatments for brain tumors, especially gliomas
- Difficulty in synthesizing stereodefined polycyclic compounds with quaternary centers
Benefits
- Potential for improved treatment options for brain tumors
- Synthetic methods for preparing these compounds can be used in other applications as well
Original Abstract Submitted
the present disclosure relates to stereodefined polycyclic (e.g., tetracyclic) compounds that contain quaternary centers at one or multiple ring fusions, synthetic methods for preparing such compounds, and methods of using such compounds to treat a disease, such as a brain tumor and, particularly, a glioma.
