18503556. COMPOUNDS AND METHODS FOR TREATING CANCER simplified abstract (DANA-FARBER CANCER INSTITUTE, INC.)
Contents
- 1 COMPOUNDS AND METHODS FOR TREATING CANCER
- 1.1 Organization Name
- 1.2 Inventor(s)
- 1.3 COMPOUNDS AND METHODS FOR TREATING CANCER - A simplified explanation of the abstract
- 1.4 Simplified Explanation
- 1.5 Potential Applications
- 1.6 Problems Solved
- 1.7 Benefits
- 1.8 Potential Commercial Applications
- 1.9 Possible Prior Art
- 1.10 Original Abstract Submitted
COMPOUNDS AND METHODS FOR TREATING CANCER
Organization Name
DANA-FARBER CANCER INSTITUTE, INC.
Inventor(s)
James Bradner of Weston MA (US)
COMPOUNDS AND METHODS FOR TREATING CANCER - A simplified explanation of the abstract
This abstract first appeared for US patent application 18503556 titled 'COMPOUNDS AND METHODS FOR TREATING CANCER
Simplified Explanation
The present application relates to compounds comprising an ester, a thioester, or a hydrazide moiety and methods of synthesizing these compounds. The present application also relates to pharmaceutical compositions containing the compounds and methods of treating cell proliferative disorders mediated by the Hedgehog (Hh) signaling pathway, such as cancer, by administering the compounds and pharmaceutical compositions to subjects in need thereof.
- Compounds with ester, thioester, or hydrazide moiety
- Methods of synthesizing compounds
- Pharmaceutical compositions for treating cell proliferative disorders
- Treatment of disorders mediated by the Hedgehog signaling pathway
Potential Applications
The compounds and pharmaceutical compositions can be used in the treatment of various cell proliferative disorders, including cancer, by targeting the Hedgehog signaling pathway.
Problems Solved
These compounds offer a potential solution for treating cell proliferative disorders by inhibiting the Hedgehog signaling pathway, which is often dysregulated in cancer and other diseases.
Benefits
The compounds provide a targeted approach to treating cell proliferative disorders, potentially offering more effective and specific treatment options for patients in need.
Potential Commercial Applications
The technology could be developed into novel pharmaceutical drugs for the treatment of cancer and other cell proliferative disorders, offering a new avenue for drug development in this area.
Possible Prior Art
One possible prior art could be the use of Hedgehog pathway inhibitors in cancer treatment, but the specific compounds with ester, thioester, or hydrazide moieties may be a novel approach in this field.
Unanswered Questions
== How do these compounds compare to existing Hedgehog pathway inhibitors in terms of efficacy and safety? These compounds with ester, thioester, or hydrazide moieties may offer advantages over existing inhibitors in terms of specificity and potency, but further studies would be needed to compare their efficacy and safety profiles.
== What are the potential side effects of targeting the Hedgehog signaling pathway with these compounds? While targeting the Hedgehog signaling pathway can be effective in treating cell proliferative disorders, there may be potential side effects associated with inhibiting this pathway, such as developmental issues or resistance development. Further research would be needed to assess the safety profile of these compounds.
Original Abstract Submitted
The present application relates to compounds comprising an ester, a thioester, or a hydrazide moiety and methods of synthesizing these compounds. The present application also relates to pharmaceutical compositions containing the compounds and methods of treating cell proliferative disorders mediated by the Hedgehog (Hh) signaling pathway, such as cancer, by administering the compounds and pharmaceutical compositions to subjects in need thereof.
