18463589. TARGETED NON-VIRAL DNA INSERTIONS simplified abstract (The Regents of the University of California)
Contents
- 1 TARGETED NON-VIRAL DNA INSERTIONS
- 1.1 Organization Name
- 1.2 Inventor(s)
- 1.3 TARGETED NON-VIRAL DNA INSERTIONS - A simplified explanation of the abstract
- 1.4 Simplified Explanation
- 1.5 Potential Applications
- 1.6 Problems Solved
- 1.7 Benefits
- 1.8 Potential Commercial Applications
- 1.9 Possible Prior Art
- 1.10 Unanswered Questions
- 1.11 Original Abstract Submitted
TARGETED NON-VIRAL DNA INSERTIONS
Organization Name
The Regents of the University of California
Inventor(s)
Theodore Lee Roth of San Francisco CA (US)
Alexander Marson of San Francisco CA (US)
TARGETED NON-VIRAL DNA INSERTIONS - A simplified explanation of the abstract
This abstract first appeared for US patent application 18463589 titled 'TARGETED NON-VIRAL DNA INSERTIONS
Simplified Explanation
The patent application describes methods and compositions for editing the genome of a cell by inserting a nucleotide sequence of at least 200 nucleotides into a target region in the cell's genome.
- Genome editing technology
- Insertion of nucleotide sequence into target region of cell's genome
Potential Applications
The technology can be used in various fields such as:
- Biomedical research
- Gene therapy
- Agriculture
Problems Solved
This technology helps in:
- Targeted gene editing
- Precision medicine
- Crop improvement
Benefits
The benefits of this technology include:
- Enhanced understanding of genetic mechanisms
- Potential treatment for genetic disorders
- Increased crop yield and quality
Potential Commercial Applications
The technology can be applied in:
- Biotech companies
- Pharmaceutical industry
- Agriculture sector
Possible Prior Art
One example of prior art in genome editing is the CRISPR-Cas9 system, which has been widely used for gene editing in various organisms.
Unanswered Questions
How efficient is the insertion of the nucleotide sequence into the target region of the cell's genome?
The efficiency of this process can vary depending on the specific method used and the characteristics of the target cell.
What are the potential off-target effects of genome editing using this method?
Off-target effects refer to unintended changes in the genome that can occur during the editing process. Further research is needed to fully understand and minimize these effects.
Original Abstract Submitted
Provided herein are methods and compositions for editing the genome of a cell. In some embodiments, a nucleotide sequence of at least 200 nucleotides in length is inserted into a target region in the genome of a cell.
