18359793. Novel Peptide Carrier Compositions simplified abstract (THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE)

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Novel Peptide Carrier Compositions

Organization Name

THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE

Inventor(s)

Uday Kompella of Centennial CO (US)

Arun Upadhyay of West Chester PA (US)

Novel Peptide Carrier Compositions - A simplified explanation of the abstract

This abstract first appeared for US patent application 18359793 titled 'Novel Peptide Carrier Compositions

Simplified Explanation

The present invention describes peptides, peptide carriers, peptide nanobodies, and peptide-drug covalent conjugates with efficient cell and tissue penetration capabilities. These configurations can be used in conjunction with therapeutic agents to enhance their delivery to tissues, cells, and intracellular spaces. Additionally, they can improve binding to negatively charged matrices in the body for better localization or retention of therapeutic carriers and agents.

  • Peptides, peptide carriers, peptide nanobodies, and peptide-drug covalent conjugates described in the invention have efficient cell and tissue penetration capabilities.
  • These configurations can be used with therapeutic agents to enhance their delivery to tissues, cells, and intracellular spaces.
  • They can improve binding to negatively charged matrices in the body for better localization or retention of therapeutic carriers and agents.

Potential Applications

The technology described in this patent application could have potential applications in the fields of drug delivery, targeted therapy, and biomedical research.

Problems Solved

This technology addresses the challenge of efficiently delivering therapeutic agents to specific tissues, cells, and intracellular spaces, as well as improving the binding and retention of therapeutic carriers in the body.

Benefits

The benefits of this technology include enhanced delivery of therapeutic agents, improved targeting of specific tissues or cells, and increased retention of therapeutic carriers in the body.

Potential Commercial Applications

The potential commercial applications of this technology could include the development of novel drug delivery systems, targeted therapies for various diseases, and advancements in biomedical research.

Possible Prior Art

One possible prior art in this field could be the use of various peptide carriers and conjugates for drug delivery purposes. However, the specific configurations and capabilities described in this patent application may represent a novel advancement in the field.

Unanswered Questions

How cost-effective is the production of these peptide configurations compared to existing drug delivery systems?

The cost-effectiveness of producing these peptide configurations compared to traditional drug delivery systems is not addressed in the patent application. Further research and analysis would be needed to determine the economic feasibility of implementing this technology on a larger scale.

What potential side effects or limitations could arise from using these peptide configurations in drug delivery?

The potential side effects or limitations of using these peptide configurations in drug delivery are not discussed in detail in the patent application. Additional studies and clinical trials would be necessary to evaluate the safety and efficacy of these configurations in practical applications.


Original Abstract Submitted

The present invention describes peptides, peptides carriers, peptide nanobodies, and peptide-drug covalent conjugates having efficient cell and tissue penetration. The peptides and associated configurations can be used in covalent attachments or as complexes or nanoparticles in conjunction with therapeutic agents to enhance their tissue, cellular, and intracellular delivery. Also, the peptides and associated configurations can enhance binding to negatively charged matrices in the body for improved localization or retention of therapeutic carriers and agents.