18274307. Regulation of Butyrophilin subfamily 3 member A1 (BTN3A1, CD277) simplified abstract (The Regents of the University of California)

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Regulation of Butyrophilin subfamily 3 member A1 (BTN3A1, CD277)

Organization Name

The Regents of the University of California

Inventor(s)

Alexander Marson of San Francisco CA (US)

Murad Mamedov of San Francisco CA (US)

Regulation of Butyrophilin subfamily 3 member A1 (BTN3A1, CD277) - A simplified explanation of the abstract

This abstract first appeared for US patent application 18274307 titled 'Regulation of Butyrophilin subfamily 3 member A1 (BTN3A1, CD277)

Simplified Explanation

Described herein are positive and negative regulators of BTN3A, as well as methods for identifying subjects who can benefit from T cell therapies and/or various chemotherapies. The subjects can, for example, be suffering from immune disorders, cancer, and other diseases and conditions.

  • Positive and negative regulators of BTN3A identified
  • Methods for identifying subjects who can benefit from T cell therapies and/or chemotherapies developed

Potential Applications

This technology could be applied in the following areas:

  • Personalized medicine for immune disorders, cancer, and other diseases
  • Development of targeted T cell therapies
  • Optimization of chemotherapy treatments

Problems Solved

This technology addresses the following issues:

  • Identifying suitable candidates for T cell therapies and chemotherapies
  • Improving treatment outcomes for immune disorders and cancer
  • Personalizing treatment plans based on individual genetic markers

Benefits

The benefits of this technology include:

  • Enhanced efficacy of T cell therapies and chemotherapies
  • Tailored treatment plans for patients
  • Improved patient outcomes and quality of life

Potential Commercial Applications

The potential commercial applications of this technology include:

  • Pharmaceutical companies developing targeted therapies
  • Diagnostic companies offering genetic testing services
  • Healthcare providers offering personalized treatment plans

Possible Prior Art

One possible prior art in this field is the identification of biomarkers for predicting response to immunotherapy in cancer patients. This research laid the foundation for personalized medicine approaches in oncology.

Unanswered Questions

How does this technology compare to existing methods for identifying suitable candidates for T cell therapies and chemotherapies?

This article does not provide a direct comparison with current diagnostic techniques or biomarker assays used in clinical practice.

What are the potential limitations or challenges in implementing this technology in a clinical setting?

The article does not address the practical considerations or regulatory hurdles that may arise when translating this research into clinical applications.


Original Abstract Submitted

Described herein are positive and negative regulators of BTN3A, as well as methods for identifying subjects who can benefit from T cell therapies and/or various chemotherapies. The subjects can for example be suffering from immune disorders, cancer and other diseases and conditions.