18261591. COLLOIDAL CRYSTAL MICRONEEDLE PATCH FOR GLUCOSE MONITORING simplified abstract (THE REGENTS OF THE UNIVERSITY OF CALIFORNIA)

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COLLOIDAL CRYSTAL MICRONEEDLE PATCH FOR GLUCOSE MONITORING

Organization Name

THE REGENTS OF THE UNIVERSITY OF CALIFORNIA

Inventor(s)

Zhen Gu of Los Angeles CA (US)

Yi Zeng of Los Angeles CA (US)

COLLOIDAL CRYSTAL MICRONEEDLE PATCH FOR GLUCOSE MONITORING - A simplified explanation of the abstract

This abstract first appeared for US patent application 18261591 titled 'COLLOIDAL CRYSTAL MICRONEEDLE PATCH FOR GLUCOSE MONITORING

Simplified Explanation

The minimally invasive glucose-responsive colloidal crystal microneedle (GCC-MN) patch is designed for naked-eye glucose monitoring. The patch consists of a resin or polymeric core that supports a shell of glucose-responsive colloidal crystal material for sensing and reporting glucose concentrations.

  • The GCC-MN patch translates glucose concentrations into naked-eye distinguishable color changes within about 5 minutes.
  • The glucose responsiveness of the patch is reversible.
  • The patch allows for interstitial fluid extraction, glucose sensing, and display of glucose-relevant colors simultaneously.

Potential Applications

The GCC-MN patch could be used in various applications such as:

  • Continuous glucose monitoring for diabetic patients
  • Research studies on glucose levels in different populations
  • Monitoring glucose levels in athletes during training and competitions

Problems Solved

The GCC-MN patch addresses the following issues:

  • Invasive blood glucose monitoring methods
  • Delayed glucose monitoring results
  • Lack of real-time glucose monitoring solutions

Benefits

The benefits of the GCC-MN patch include:

  • Minimally invasive glucose monitoring
  • Rapid and reversible glucose sensing
  • Naked-eye distinguishable color changes for easy interpretation

Potential Commercial Applications

The GCC-MN patch has potential commercial applications in:

  • Medical device industry
  • Healthcare sector
  • Biotechnology companies

Possible Prior Art

One possible prior art for this technology could be the development of other glucose-responsive microneedle patches for glucose monitoring. However, the specific design and features of the GCC-MN patch may distinguish it from existing technologies.

Unanswered Questions

How does the GCC-MN patch compare to traditional glucose monitoring methods in terms of accuracy and reliability?

The article does not provide a direct comparison between the GCC-MN patch and traditional glucose monitoring methods. Further research or clinical trials may be needed to evaluate the accuracy and reliability of the patch compared to existing methods.

What is the cost-effectiveness of implementing the GCC-MN patch for glucose monitoring on a large scale?

The article does not discuss the cost-effectiveness of mass-producing and distributing the GCC-MN patch for widespread use. Economic analyses or market studies may be required to assess the financial implications of adopting this technology on a larger scale.


Original Abstract Submitted

A minimally invasive glucose-responsive colloidal crystal microneedle (GCC-MN) patch is disclosed for naked-eye glucose monitoring. The (GCC-MN) patch is designed with a resin or polymeric core to mechanically support a shell of glucose-responsive colloidal crystal material for glucose sensing and reporting of glucose concentrations or concentration changes. The GCC-MN patch could translate the glucose concentrations into naked-eye distinguishable color changes within about 5 min, and such glucose responsiveness is reversible. Demonstrated in a type 1 diabetic mouse model, the interstitial fluid extraction, glucose sensing, and resulting glucose-relevant color display procedures are simultaneously achieved with this GCC-MN patch.