17980315. NANOSTRUCTURED SYSTEM FOR FLUOROMETRIC NUCLEIC ACID AMPLIFICATION simplified abstract (Samsung Electronics Co., Ltd.)

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NANOSTRUCTURED SYSTEM FOR FLUOROMETRIC NUCLEIC ACID AMPLIFICATION

Organization Name

Samsung Electronics Co., Ltd.

Inventor(s)

Vinayak Narasimhan of Altadena CA (US)

Radwanul Hasan Siddique of Monrovia CA (US)

Wonjong Jung of Seoul (KR)

Kak Namkoong of Seoul (KR)

Youngzoon Yoon of Kyonggi-do (KR)

NANOSTRUCTURED SYSTEM FOR FLUOROMETRIC NUCLEIC ACID AMPLIFICATION - A simplified explanation of the abstract

This abstract first appeared for US patent application 17980315 titled 'NANOSTRUCTURED SYSTEM FOR FLUOROMETRIC NUCLEIC ACID AMPLIFICATION

Simplified Explanation

The patent application describes an amplification reaction chamber for nucleic acid (NA) amplification in a gene analysis system. The chamber includes a multi-layered nanostructure coating that enhances fluorescence in the NA amplification reaction.

  • The amplification reaction chamber has an interior surface where the NA amplification reaction takes place.
  • A multi-layered nanostructure coating is applied to at least a portion of the interior surface.
  • The nanostructure coating includes sub-micrometer nanostructures that enhance fluorescence in the NA amplification reaction.
  • The enhancement of fluorescence is based on the plasmonic material of the nanostructures and their geometric dimensions.

Potential applications of this technology:

  • Gene analysis systems
  • Medical diagnostics
  • Forensic analysis
  • Environmental testing

Problems solved by this technology:

  • Improved sensitivity and accuracy in nucleic acid amplification reactions
  • Enhanced fluorescence signals for better detection of target sequences
  • Reduction of background noise in gene analysis systems

Benefits of this technology:

  • Increased efficiency in gene analysis processes
  • Enhanced performance in nucleic acid amplification reactions
  • Improved reliability and accuracy in detecting specific DNA sequences


Original Abstract Submitted

An amplification reaction chamber and a method for nucleic acid (NA) amplification in a gene analysis system are provided. The amplification reaction chamber includes an interior surface within which an NA amplification reaction is performed. The amplification reaction chamber also includes a multi-layered nanostructure coating conformally applied to at least a portion of the interior surface and including sub-micrometer nanostructures that enhance fluorescence in the NA amplification reaction based on at least one of plasmonic material of which the sub-micrometer nanostructures are made and geometric dimensions of the sub-micrometer nanostructures.