17828332. RECOMBINANT MICROORGANISM HAVING ENHANCED ABILITY TO REMOVE NITRIC OXIDE AND USE THEREOF simplified abstract (Samsung Electronics Co., Ltd.)
RECOMBINANT MICROORGANISM HAVING ENHANCED ABILITY TO REMOVE NITRIC OXIDE AND USE THEREOF
Organization Name
Inventor(s)
Yu Kyung Jung of Hwaseong-si (KR)
Jae-Young Kim of Suwon-si (KR)
Seung Hoon Song of Suwon-si (KR)
Woo Yong Shim of Hwaseong-si (KR)
RECOMBINANT MICROORGANISM HAVING ENHANCED ABILITY TO REMOVE NITRIC OXIDE AND USE THEREOF - A simplified explanation of the abstract
This abstract first appeared for US patent application 17828332 titled 'RECOMBINANT MICROORGANISM HAVING ENHANCED ABILITY TO REMOVE NITRIC OXIDE AND USE THEREOF
Simplified Explanation
The abstract of the patent application describes a recombinant microorganism that has been genetically modified to increase the expression of certain genes or decrease the expression of another gene. This modification allows the microorganism to remove greater amounts of nitric oxide from a sample compared to a microorganism without the genetic modification.
- The recombinant microorganism has a genetic modification that increases the expression of a gene encoding a ferric enterobactin transporter-associated protein or a gene encoding a TonB-dependent transporter-associated protein.
- Alternatively, the recombinant microorganism has a genetic modification that decreases the expression of a fur gene encoding a ferric uptake regulator (Fur) protein.
- The genetic modification enables the microorganism to remove larger quantities of nitric oxide from a sample containing nitric oxide.
- The microorganism without the genetic modification is not as effective in removing nitric oxide.
Potential Applications
- Environmental remediation: The recombinant microorganism can be used to remove nitric oxide from polluted air or water sources.
- Biomedical applications: The microorganism can be utilized to reduce nitric oxide levels in patients with conditions related to nitric oxide imbalance, such as sepsis or inflammation.
Problems Solved
- Nitric oxide is a harmful pollutant and excessive levels can have detrimental effects on the environment and human health. The genetic modification of the microorganism allows for more efficient removal of nitric oxide, addressing the problem of nitric oxide pollution.
Benefits
- Increased nitric oxide removal: The recombinant microorganism is more effective at removing nitric oxide compared to non-modified microorganisms.
- Versatile application: The technology can be applied in various fields, including environmental remediation and biomedical applications.
- Potential for cost-effectiveness: The use of genetically modified microorganisms may provide a cost-effective solution for nitric oxide removal compared to other methods.
Original Abstract Submitted
A recombinant microorganism including a genetic modification that increases expression of a gene encoding a ferric enterobactin transporter-associated protein or a gene encoding a TonB-dependent transporter-associated protein, or a genetic modification that decreases expression of a fur gene encoding a ferric uptake regulator (Fur) protein, wherein the recombinant microorganism removes greater amounts of nitric oxide from a sample comprising nitric oxide than a same microorganism without the genetic modification
