17769171. COMPOSITIONS AND METHODS FOR DETECTING PLXDC1 AND PLXCD2 IN HUMAN TISSUES simplified abstract (The Regents of the University of California)

COMPOSITIONS AND METHODS FOR DETECTING PLXDC1 AND PLXCD2 IN HUMAN TISSUES

Organization Name

The Regents of the University of California

Inventor(s)

Hui Sun of Los Angeles CA (US)

Adrian Chichuen Au of Los Angeles CA (US)

Guo Cheng of Los Angeles CA (US)

COMPOSITIONS AND METHODS FOR DETECTING PLXDC1 AND PLXCD2 IN HUMAN TISSUES - A simplified explanation of the abstract

This abstract first appeared for US patent application 17769171 titled 'COMPOSITIONS AND METHODS FOR DETECTING PLXDC1 AND PLXCD2 IN HUMAN TISSUES

Simplified Explanation

The present disclosure is about methods for preparing a tissue sample for detecting the expression of transmembrane proteins PLXDC1 or PLXDC2, as well as providing antibodies and treatments for tumor samples expressing these proteins.

• Detection of transmembrane protein expression in tissue samples
• Targeting tumor samples expressing PLXDC1 or PLXDC2 proteins with antibodies and treatments

Potential Applications

This technology could be used in:

• Cancer research
• Drug development targeting PLXDC1 and PLXDC2 proteins

Problems Solved

This technology helps in:

• Identifying transmembrane protein expression in tissue samples
• Targeting tumor samples expressing specific proteins for treatment

Benefits

The benefits of this technology include:

• Improved detection of transmembrane protein expression
• Targeted treatments for tumors expressing PLXDC1 or PLXDC2 proteins

Potential Commercial Applications

A potential commercial application of this technology could be:

• Developing diagnostic tools for detecting transmembrane protein expression in tumors

Possible Prior Art

One possible prior art could be:

• Methods for detecting protein expression in tissue samples using immunohistochemistry

What are the specific methods for preparing a tissue sample for detection of transmembrane protein expression?

The specific methods for preparing a tissue sample for detection of transmembrane protein expression involve sample collection, processing, and analysis using techniques such as immunohistochemistry.

How do the antibodies and treatments target tumor samples expressing PLXDC1 or PLXDC2 proteins?

The antibodies and treatments target tumor samples expressing PLXDC1 or PLXDC2 proteins by specifically binding to these proteins and inhibiting their function, leading to potential therapeutic effects.

Original Abstract Submitted

The present disclosure relates generally to methods for preparing a tissue sample for detection of the expression of a transmembrane protein in the tissue sample. The present disclosure also provides antibodies and treatments targeting tumor samples expressing the PLXDC1 or the PLXDC2 proteins.