View source for 20240016439. GENERATING FUNCTIONAL BRAIN MAPPINGS AND ACCOMPANYING REFERENCE INFORMATION simplified abstract (SORA NEUROSCIENCE, INC.)

=GENERATING FUNCTIONAL BRAIN MAPPINGS AND ACCOMPANYING REFERENCE INFORMATION=


==Organization Name==

[[:Category:SORA NEUROSCIENCE, INC.|SORA NEUROSCIENCE, INC.]]


[[Category:SORA NEUROSCIENCE, INC.]]

==Inventor(s)==

[[:Category:Eric C. Leuthardt of St. Louis MO (US)|Eric C. Leuthardt of St. Louis MO (US)]][[Category:Eric C. Leuthardt of St. Louis MO (US)]]

[[:Category:Connor J. Burns of Louisville KY (US)|Connor J. Burns of Louisville KY (US)]][[Category:Connor J. Burns of Louisville KY (US)]]

[[:Category:Patrick R. Campbell of Maryville TN (US)|Patrick R. Campbell of Maryville TN (US)]][[Category:Patrick R. Campbell of Maryville TN (US)]]

[[:Category:Carl D. Hacker of St. Louis MO (US)|Carl D. Hacker of St. Louis MO (US)]][[Category:Carl D. Hacker of St. Louis MO (US)]]

[[:Category:Stephen R. Schaefer of Minneapolis MN (US)|Stephen R. Schaefer of Minneapolis MN (US)]][[Category:Stephen R. Schaefer of Minneapolis MN (US)]]

==GENERATING FUNCTIONAL BRAIN MAPPINGS AND ACCOMPANYING REFERENCE INFORMATION - A simplified explanation of the abstract==


This abstract first appeared for US patent application 20240016439 titled 'GENERATING FUNCTIONAL BRAIN MAPPINGS AND ACCOMPANYING REFERENCE INFORMATION

==Simplified Explanation==

The patent application describes a method for mapping functionally related brain regions of a subject using structural brain images and resting-state functional MRI (rs-fMRI) data. The method involves identifying groupings of functionally connected voxels and overlaying them on the structural brain image. The spontaneous brain activations of each voxel in a grouping are correlated with the activations of other voxels in the same grouping. A reference location map is generated to assist in identifying the resting state network of the functional connectivity map.

* The method uses structural brain images and rs-fMRI data to map functionally related brain regions.
* Groupings of functionally connected voxels are identified and overlaid on the structural brain image.
* The method correlates the spontaneous brain activations of voxels within a grouping.
* A reference location map is generated to assist in identifying the resting state network of the functional connectivity map.

Potential applications of this technology:
* Understanding brain connectivity and functional networks in healthy individuals.
* Identifying abnormalities or disruptions in brain connectivity in neurological disorders.
* Guiding surgical planning by mapping functional brain regions.

Problems solved by this technology:
* Provides a non-invasive method for mapping functionally related brain regions.
* Allows for the identification of resting state networks and their connectivity patterns.
* Helps in understanding the functional organization of the brain.

Benefits of this technology:
* Provides valuable insights into the functional connectivity of the brain.
* Can aid in the diagnosis and treatment of neurological disorders.
* Enables personalized medicine by mapping individual brain networks.


==Original Abstract Submitted==

a method for mapping functionally related brain regions of a subject. the method includes receiving a structural brain image and a dataset of resting-state functional mri (rs-fmr1) three-dimensional (3d) image frames of a brain of the subject includes 3d image frames of the subject's brain over time. a functional connectivity map identifying groupings of functionally connected voxels is overlaid on the structural brain image. spontaneous brain activations associated with each voxel in a grouping of functionally connected voxels are time-correlated with spontaneous brain activations in one or more other voxels in the grouping of functionally connected voxels. a reference location map for a pre-defined resting state network is generated, including reference information output. the reference location map includes brain reference locations that are informative of the one or more resting-state networks to assist a user in identifying the resting state network of the functional connectivity map.



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