18288245. HIGH-THROUGHPUT EXPRESSION-LINKED PROMOTER SELECTION IN EUKARYOTIC CELLS simplified abstract (The Regents of the University of California)
Contents
HIGH-THROUGHPUT EXPRESSION-LINKED PROMOTER SELECTION IN EUKARYOTIC CELLS
Organization Name
The Regents of the University of California
Inventor(s)
David V. Schaffer of Berkeley CA (US)
Joost Van Haasteren of Berkeley CA (US)
Kazuomori Lewis of Berkeley CA (US)
HIGH-THROUGHPUT EXPRESSION-LINKED PROMOTER SELECTION IN EUKARYOTIC CELLS - A simplified explanation of the abstract
This abstract first appeared for US patent application 18288245 titled 'HIGH-THROUGHPUT EXPRESSION-LINKED PROMOTER SELECTION IN EUKARYOTIC CELLS
The present disclosure introduces methods for creating synthetic transcriptional promoters that work in eukaryotic cells. It also includes libraries of expression vectors containing these synthetic promoters and the process for generating these libraries. Additionally, the disclosure provides synthetic transcriptional promoters that are functional in eukaryotic cells, as well as recombinant expression vectors incorporating these promoters.
- Methods for generating synthetic transcriptional promoters functional in eukaryotic cells
- Libraries of expression vectors with synthetic promoters for eukaryotic cells
- Creation of synthetic transcriptional promoters that work in eukaryotic cells
- Recombinant expression vectors containing synthetic transcriptional promoters
Potential Applications: The technology can be used in genetic engineering, biotechnology, and pharmaceutical research for controlling gene expression in eukaryotic cells.
Problems Solved: This technology addresses the need for precise control over gene expression in eukaryotic cells, allowing researchers to study gene function and develop new therapies.
Benefits: - Enhanced control over gene expression - Facilitates research in genetic engineering and biotechnology - Potential for developing novel treatments for diseases
Commercial Applications: The technology can be utilized in pharmaceutical companies, biotech firms, and research institutions for drug discovery, gene therapy development, and bioproduction processes.
Questions about Synthetic Transcriptional Promoters: 1. How do synthetic transcriptional promoters differ from natural promoters?
Synthetic transcriptional promoters are artificially designed sequences that regulate gene expression, while natural promoters are found in the genome and control the expression of specific genes.
2. What are the advantages of using synthetic transcriptional promoters in genetic engineering?
Synthetic transcriptional promoters offer precise control over gene expression levels, allowing researchers to fine-tune gene regulation for various applications.
Original Abstract Submitted
The present disclosure provides methods for generating synthetic transcriptional promoters that are functional in a eukaryotic cell. The present disclosure provides libraries of expression vectors comprising synthetic transcriptional promoters that are functional in a eukaryotic cell; and methods for generating the libraries. The present disclosure provides synthetic transcriptional promoters that are functional in a eukaryotic cell; as well as recombinant expression vectors comprising the synthetic transcriptional promoters.