18525119. CELL CULTURE VESSEL simplified abstract (CORNING INCORPORATED)

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CELL CULTURE VESSEL

Organization Name

CORNING INCORPORATED

Inventor(s)

William Joseph Lacey of North Andover MA (US)

Gregory Roger Martin of Acton ME (US)

Ana Maria del Pilar Pardo of Portsmouth NH (US)

Allison Jean Tanner of Portsmouth NH (US)

CELL CULTURE VESSEL - A simplified explanation of the abstract

This abstract first appeared for US patent application 18525119 titled 'CELL CULTURE VESSEL

Simplified Explanation

The cell culture vessel described in the patent application provides a unique environment for culturing cells in three-dimensional conformation, known as "spheroids." The vessel has a cell culture surface with microcavities, creating a chamber for cell culture without flat surfaces, promoting the production of homogeneous cell clusters.

  • Microcavities on the cell culture surface promote the formation of three-dimensional cell clusters.
  • The vessel design eliminates flat surfaces around the cell culture surface to support spheroid production.

Potential Applications

The technology could be applied in tissue engineering, drug screening, and regenerative medicine research.

Problems Solved

This technology addresses the challenge of creating homogeneous three-dimensional cell clusters for various research and applications.

Benefits

The vessel allows for the production of spheroids in a controlled environment, enabling more accurate and reliable cell culture experiments.

Potential Commercial Applications

The technology could be utilized in pharmaceutical companies, research institutions, and biotechnology firms for drug development and regenerative medicine research.

Possible Prior Art

There may be prior art related to cell culture vessels with microcavities for three-dimensional cell culture, but specific examples are not provided in this context.

Unanswered Questions

How does this technology compare to traditional cell culture methods in terms of efficiency and scalability?

The efficiency and scalability of this technology compared to traditional cell culture methods are not addressed in the provided information. Further research or data may be needed to make a comparison.

What are the potential limitations or challenges in implementing this technology in large-scale cell culture production?

The potential limitations or challenges in implementing this technology for large-scale cell culture production are not discussed in the abstract. Additional information or studies may be required to assess these aspects.


Original Abstract Submitted

A cell culture vessel has a wall and cell culture surface having a plurality of microcavities for culturing cells in three-dimensional conformation, referred to as “spheroids”. The inner surface of the wall and the cell culture surface define a cell culture chamber of the vessel. The wall is attached to the cell culture surface in a way that does not provide flat surfaces on or around the cell culture surface so that the vessel provides an environment suitable for the production of a homogeneous population of three-dimensional cell clusters, or spheroids.