18481700. ACCELERATING CUTANEOUS HEALING UTILIZING NON-INVASIVE FOCUSED ULTRASOUND simplified abstract (General Electric Company)

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ACCELERATING CUTANEOUS HEALING UTILIZING NON-INVASIVE FOCUSED ULTRASOUND

Organization Name

General Electric Company

Inventor(s)

Christine A. Morton of Mechanicville NY (US)

Christopher Michael Puleo of Niskayuna NY (US)

Jeffrey Michael Ashe of Gloversville NY (US)

Victoria Eugenia Cotero of Troy NY (US)

ACCELERATING CUTANEOUS HEALING UTILIZING NON-INVASIVE FOCUSED ULTRASOUND - A simplified explanation of the abstract

This abstract first appeared for US patent application 18481700 titled 'ACCELERATING CUTANEOUS HEALING UTILIZING NON-INVASIVE FOCUSED ULTRASOUND

Simplified Explanation

The present invention relates to a method of promoting wound healing using pulsed focused ultrasound to modulate immune cells and promote migration to the wound bed.

  • Ultrasound transducer positioned at stimulation site on subject with wound
  • Pulsed focused ultrasound applied non-invasively to modulate immune cells
  • Modulation causes migration of monocytes, macrophages, or neutrophils to wound bed

Potential Applications

This technology could be applied in the medical field for the treatment of chronic wounds, diabetic ulcers, and other slow-healing wounds.

Problems Solved

This technology addresses the issue of slow healing wounds and persistent chronic wounds by promoting the migration of immune cells to the wound bed, which can help accelerate the healing process.

Benefits

The use of pulsed focused ultrasound to modulate immune cells offers a non-invasive and potentially effective method for promoting wound healing in patients with chronic wounds.

Potential Commercial Applications

This technology could have commercial applications in the development of medical devices for wound healing, as well as in the field of regenerative medicine for tissue repair and regeneration.

Possible Prior Art

Prior art may include other methods of using ultrasound for wound healing, such as low-intensity ultrasound therapy or high-intensity focused ultrasound for tissue ablation.

What are the potential side effects of using pulsed focused ultrasound for wound healing?

Potential side effects of using pulsed focused ultrasound for wound healing may include skin irritation, burns, or discomfort at the stimulation site. It is important to carefully monitor patients during treatment to minimize the risk of adverse reactions.

How does the modulation of immune cells using pulsed focused ultrasound compare to other methods of promoting wound healing?

Modulating immune cells using pulsed focused ultrasound offers a non-invasive approach to promoting wound healing, which may be more convenient and comfortable for patients compared to other methods such as surgery or medication. Additionally, this method specifically targets immune cells involved in the healing process, potentially leading to more targeted and effective results.


Original Abstract Submitted

The present approaches are generally directed to facilitating healing of wounds, including chronic wounds typically associated with slow heal times or which are persistent. In one embodiment, a method of promoting wound healing comprises positioning an ultrasound transducer at a stimulation site on a subject having a wound. Pulsed focused ultrasound (pFUS) is non-invasively applies using the transducer to cause modulation of a target anatomic site containing resident or circulating immune cells. Modulation of the target anatomic site of the subject causes migration of one or more of monocytes, macrophages, or neutrophils to a wound bed of the wound.