18477010. COMPOSITIONS, SYSTEMS, AND METHODS FOR TREATING CANCER USING ALTERNATING ELECTRIC FIELDS AND DENDRITIC CELLS simplified abstract (Novocure GmbH)
Contents
- 1 COMPOSITIONS, SYSTEMS, AND METHODS FOR TREATING CANCER USING ALTERNATING ELECTRIC FIELDS AND DENDRITIC CELLS
- 1.1 Organization Name
- 1.2 Inventor(s)
- 1.3 COMPOSITIONS, SYSTEMS, AND METHODS FOR TREATING CANCER USING ALTERNATING ELECTRIC FIELDS AND DENDRITIC CELLS - A simplified explanation of the abstract
- 1.4 Simplified Explanation
- 1.5 Potential Applications
- 1.6 Problems Solved
- 1.7 Benefits
- 1.8 Potential Commercial Applications
- 1.9 Possible Prior Art
- 1.10 How does the alternating electric field specifically activate dendritic cells in the proposed method?
- 1.11 What are the potential side effects or limitations of using an alternating electric field in vivo or ex vivo for medical purposes?
- 1.12 Original Abstract Submitted
COMPOSITIONS, SYSTEMS, AND METHODS FOR TREATING CANCER USING ALTERNATING ELECTRIC FIELDS AND DENDRITIC CELLS
Organization Name
Inventor(s)
Tali Voloshin-sela of Haifa (IL)
Yiftah Barsheshet of Haifa (IL)
IIan Volovitz of Tel Aviv (IL)
COMPOSITIONS, SYSTEMS, AND METHODS FOR TREATING CANCER USING ALTERNATING ELECTRIC FIELDS AND DENDRITIC CELLS - A simplified explanation of the abstract
This abstract first appeared for US patent application 18477010 titled 'COMPOSITIONS, SYSTEMS, AND METHODS FOR TREATING CANCER USING ALTERNATING ELECTRIC FIELDS AND DENDRITIC CELLS
Simplified Explanation
The patent application describes compositions, systems, and methods for activating dendritic cells, reducing the viability of cancer cells, treating cancer, preventing tumor growth, and treating other diseases and infections through the application of an alternating electric field.
- Activating dendritic cells through exposure to an alternating electric field
- Reducing cancer cell viability and treating cancer
- Preventing tumor growth in living subjects
- Treating other diseases and infections
- Administering activated dendritic cells to subjects
Potential Applications
The technology could be applied in cancer treatment, immunotherapy, and infectious disease treatment.
Problems Solved
The technology addresses the challenges of cancer cell viability, tumor growth, and immune system activation in disease treatment.
Benefits
The benefits include improved cancer treatment outcomes, enhanced immune response, and potential for personalized medicine approaches.
Potential Commercial Applications
The technology could be commercialized in the fields of biotechnology, pharmaceuticals, and medical devices.
Possible Prior Art
One possible prior art could be the use of electric fields in cancer treatment, but the specific application to activating dendritic cells may be novel.
Unanswered Questions
How does the alternating electric field specifically activate dendritic cells in the proposed method?
The patent application does not provide detailed information on the mechanism of action of the alternating electric field on dendritic cells.
What are the potential side effects or limitations of using an alternating electric field in vivo or ex vivo for medical purposes?
The potential risks or drawbacks of using alternating electric fields for medical purposes are not discussed in the patent application.
Original Abstract Submitted
Compositions, systems, and methods for activating dendritic cells are disclosed. Also disclosed are compositions, systems, and methods for reducing viability of cancer cells and treating cancer, as well as preventing an increase in volume of a tumor present in a body of a living subject, along with methods of treating other diseases and infections. The systems and methods involve application of an alternating electric field to dendritic cell(s) in vivo or ex vivo and/or to a subject or cancer cells isolated therefrom. The systems and methods may further include administration of activated dendritic cells to a subject. The compositions comprise populations of isolated dendritic cells activated by exposure to an alternating electric field.