18463628. CRISPR-CAS /TRANSCRIPTION FACTOR-BASED COMPETITION ASSAY FOR DETECTION OF MOLECULAR ANALYTES simplified abstract (Arizona Board of Regents on Behalf of Arizona State University)
Contents
- 1 CRISPR-CAS /TRANSCRIPTION FACTOR-BASED COMPETITION ASSAY FOR DETECTION OF MOLECULAR ANALYTES
- 1.1 Organization Name
- 1.2 Inventor(s)
- 1.3 CRISPR-CAS /TRANSCRIPTION FACTOR-BASED COMPETITION ASSAY FOR DETECTION OF MOLECULAR ANALYTES - A simplified explanation of the abstract
- 1.4 Simplified Explanation
- 1.5 Potential Applications
- 1.6 Problems Solved
- 1.7 Benefits
- 1.8 Potential Commercial Applications
- 1.9 Possible Prior Art
- 1.10 Original Abstract Submitted
CRISPR-CAS /TRANSCRIPTION FACTOR-BASED COMPETITION ASSAY FOR DETECTION OF MOLECULAR ANALYTES
Organization Name
Arizona Board of Regents on Behalf of Arizona State University
Inventor(s)
Alexander Green of Chestnut Hill MA (US)
Soma Chaudhary of Tempe AZ (US)
Kirstie Swingle of Henrico VA (US)
CRISPR-CAS /TRANSCRIPTION FACTOR-BASED COMPETITION ASSAY FOR DETECTION OF MOLECULAR ANALYTES - A simplified explanation of the abstract
This abstract first appeared for US patent application 18463628 titled 'CRISPR-CAS /TRANSCRIPTION FACTOR-BASED COMPETITION ASSAY FOR DETECTION OF MOLECULAR ANALYTES
Simplified Explanation
The abstract describes highly modular and sensitive biosensors for small molecule detection using CRISPR/C as enzymes with collateral single-stranded nucleic acid cleavage activity. These biosensors can be used in detection platforms for convenient, low-cost assessment of safety and purity of consumable samples, environmental samples, and agricultural products.
- Biosensors for small molecule detection using CRISPR/C as enzymes
- Collateral single-stranded nucleic acid cleavage activity
- Detection platforms for safety and purity assessment of samples
- Convenient and low-cost detection methods
Potential Applications
The technology can be applied in various fields such as food safety testing, environmental monitoring, and agricultural quality control.
Problems Solved
The biosensors address the need for rapid, sensitive, and cost-effective detection methods for small molecules in different sample types.
Benefits
The biosensors offer high sensitivity, modularity, and convenience in detecting small molecules, making them valuable tools for various industries.
Potential Commercial Applications
"Low-Cost Small Molecule Detection Biosensors for Safety and Purity Assessment" technology can be utilized in industries such as food and beverage, agriculture, environmental monitoring, and pharmaceuticals.
Possible Prior Art
One possible prior art could be the development of biosensors using CRISPR/C technology for nucleic acid detection, but the specific application for small molecule detection with collateral single-stranded nucleic acid cleavage activity may be novel.
Unanswered Questions
How does this technology compare to traditional small molecule detection methods?
The article does not provide a direct comparison between this technology and traditional small molecule detection methods.
What are the limitations of using CRISPR/C as enzymes in biosensors for small molecule detection?
The article does not discuss any limitations or challenges associated with using CRISPR/C as enzymes in biosensors for small molecule detection.
Original Abstract Submitted
Provided herein are highly modular and sensitive biosensors for small molecule detection using CRISPR/C as enzymes having collateral single-stranded nucleic acid cleavage activity. Also provided herein are uses of the biosensors in detection platforms for convenient, low-cost assessment of safety and purity of consumable samples, environmental samples, and agricultural products.
