18467074. Pretreatment Of Plasma For Spray Drying And Storage simplified abstract (Velico Medical, Inc.)

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Pretreatment Of Plasma For Spray Drying And Storage

Organization Name

Velico Medical, Inc.

Inventor(s)

Lisa A. Buckley of Portland OR (US)

Mark A. Popovsky of Sharon MA (US)

Jihae Sohn of Salem MA (US)

Qiyong Peter Liu of Newton MA (US)

William J. Merritt of Danvers MA (US)

Pretreatment Of Plasma For Spray Drying And Storage - A simplified explanation of the abstract

This abstract first appeared for US patent application 18467074 titled 'Pretreatment Of Plasma For Spray Drying And Storage

Simplified Explanation

The method described in the patent application involves treating plasma with a pretreatment solution containing a physiologically compatible spray dry stable acidic substance (SDSAS) and an amino acid before or during the spray drying process. This treatment results in improved recovery and long-term stabilization of the dried plasma proteins compared to traditional methods.

  • The pretreatment solution contains a physiologically compatible SDSAS and an amino acid.
  • The treatment is applied to plasma before or during the spray drying process.
  • The method leads to greater recovery and long-term stabilization of dried plasma proteins.

Potential Applications

The technology could be applied in the pharmaceutical industry for the production of stable dried plasma products for medical use.

Problems Solved

This method addresses the challenge of maintaining the stability and integrity of dried plasma proteins during the manufacturing process.

Benefits

  • Improved recovery of dried plasma proteins
  • Enhanced long-term stabilization of plasma products
  • Potential for increased shelf life of dried plasma

Potential Commercial Applications

"Enhancing Stability of Dried Plasma Proteins for Pharmaceutical Use"

Possible Prior Art

There may be prior art related to methods of stabilizing dried plasma proteins, but the specific combination of a physiologically compatible SDSAS and an amino acid in a pretreatment solution may be novel.

Unanswered Questions

How does this method compare to other techniques for stabilizing dried plasma proteins?

This article does not provide a direct comparison with other stabilization techniques, leaving the reader to wonder about the relative effectiveness and efficiency of this method.

What are the specific physiologically compatible SDSAS and amino acids used in the pretreatment solution?

The article does not specify the exact substances used in the pretreatment solution, leaving the reader curious about the specific components and their roles in the process.


Original Abstract Submitted

A method of treating plasma with a pretreatment solution that has a physiologically compatible spray dry stable acidic substance (SDSAS) and an amino acid, prior to or contemporaneously with spray drying of the plasma that results in greater recovery and greater long-term stabilization of the dried plasma proteins as compared to spray dried plasma that has not be subject to the formulation method of the present invention, as well as compositions related to plasma dried by the methods of the present invention.