View source for 18013682. Vertical Flow Assay Device and Method for Determination of Hemoglobin Concentration simplified abstract (Google LLC)

=Vertical Flow Assay Device and Method for Determination of Hemoglobin Concentration=


==Organization Name==

[[:Category:Google LLC|Google LLC]]


[[Category:Google LLC]]

==Inventor(s)==

[[:Category:Kristy Mckeating of San Francisco CA (US)|Kristy Mckeating of San Francisco CA (US)]][[Category:Kristy Mckeating of San Francisco CA (US)]]

[[:Category:Herschel Watkins of Woodacre CA (US)|Herschel Watkins of Woodacre CA (US)]][[Category:Herschel Watkins of Woodacre CA (US)]]

==Vertical Flow Assay Device and Method for Determination of Hemoglobin Concentration - A simplified explanation of the abstract==


This abstract first appeared for US patent application 18013682 titled 'Vertical Flow Assay Device and Method for Determination of Hemoglobin Concentration

==Simplified Explanation==

The present disclosure describes an assay device for determining the concentration of hemoglobin in a sample, utilizing a separation membrane with a cell lysing reagent and a downstream detection membrane that responds to the presence of hemoglobin.

* The separation membrane contains a cell lysing reagent in a specific range of 200-675 micrograms/square centimeter.
* The detection membrane is designed with an asymmetric structure, with larger pores on the upstream side and smaller pores on the downstream side.
* The device uses vertical flow assay technology to lyse red blood cells in the sample and quantify hemoglobin levels through reflectance spectroscopy.

== Potential Applications ==
This technology could be used in medical diagnostics, blood testing, and research laboratories for quick and accurate hemoglobin level measurements.

== Problems Solved ==
This device provides a simple and efficient method for determining hemoglobin concentration in samples without the need for complex equipment or extensive sample preparation.

== Benefits ==
The device offers a rapid and reliable way to measure hemoglobin levels, which is crucial for diagnosing anemia, monitoring blood disorders, and assessing overall health.

== Potential Commercial Applications ==
* Medical device companies could incorporate this technology into portable hemoglobin testing devices for healthcare professionals.
* Research institutions could use this device for high-throughput screening of hemoglobin levels in various samples.

== Possible Prior Art ==
One possible prior art could be traditional methods of hemoglobin measurement, such as centrifugation or laboratory-based spectrophotometry techniques.

=== Unanswered Questions ===

=== How does this device compare to existing hemoglobin testing methods in terms of accuracy and speed? ===
This article does not provide a direct comparison between this device and other hemoglobin testing methods in terms of accuracy and speed.

=== What are the limitations of this device in terms of sample size and compatibility with different types of samples? ===
The article does not address the limitations of this device in terms of sample size and compatibility with various sample types.


==Original Abstract Submitted==

The present disclosure provides an assay device for determining a concentration of hemoglobin in a sample. The device includes a separation membrane containing a cell lysing reagent that is present on the separation membrane in an amount greater than 200 micrograms/square centimeter to less than 675 micrograms/square centimeter. Further, the device includes a downstream detection membrane configured to elicit a quantifiable response in the presence of hemoglobin. The detection membrane includes an asymmetric membrane having a first plurality of pores located towards an upstream side of the detection membrane and a second plurality of pores located towards a downstream side of the detection membrane. The first plurality of pores are larger than the second plurality of pores. The present disclosure also provides methods for using a vertical flow assay device to lyse the red blood cells in the sample to quantify the level of hemoglobin present via reflectance spectroscopy.



[[Category:G01N33/49]]
[[Category:B01L3/00]]
[[Category:G01N33/72]]